Home NewsAfrica UK Covid-19 patient was positive for record 505 days, researchers say | News24

UK Covid-19 patient was positive for record 505 days, researchers say | News24

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  • The longest recognized Covid-19 an infection has been documented by British researchers.
  • The affected person examined optimistic of coronavirus for 505 days earlier than her dying.
  • The affected person examined optimistic about 45 instances earlier than going to hospital.

British researchers imagine they’ve documented the longest-known Covid-19 an infection, in a affected person who examined optimistic for a complete of 505 days earlier than their dying.

The earlier report for persistent an infection – fairly than repeated bouts of Covid – is regarded as 335 days, the workforce from King’s School London and Man’s and St Thomas’ NHS Basis Belief stated.

One of many research’s co-authors, marketing consultant virologist Gaia Nebbia, stated the unnamed particular person was recognized in mid-2020 with respiratory signs that later improved.

However they then examined optimistic about 45 instances earlier than attending hospital as much as their dying.

Nebbia stated persistent an infection with SARS-CoV-2 – the virus which causes Covid-19 – has been described in sufferers with weakened immune programs.

She and her workforce studied how the virus from 9 Covid-19 sufferers in London modified over time, concluding that new variants might happen in immunocompromised sufferers.

“This is likely one of the hypotheses for the emergence of variants,” Nebbia instructed AFP.

Common sampling and genetic evaluation of the virus confirmed that 5 of the 9 sufferers developed a minimum of one mutation seen in variants of concern. Some people developed a number of mutations related to variants of concern, such because the Alpha, Delta and Omicron variants.

“Nonetheless, not one of the people in our work developed new variants that grew to become widespread variants of concern.”

Of the 9 immunocompromised sufferers who examined optimistic for a minimum of eight weeks, infections endured on common for 73 days.

However two sufferers had persistent infections for greater than a yr.

All of the sufferers had weakened immune programs resulting from organ transplantation, HIV, most cancers or different medical therapies. They have been studied between March 2020 and December final yr.

Of the 9, 5 survived. Two of the 5 recovered with out remedy and two others recovered after antibody and antiviral remedy.

The fifth particular person was nonetheless contaminated at their final follow-up examination in early 2022, even after remedy, and had Covid-19 for 412 days.

Ought to they take a look at optimistic at their subsequent appointment, they’ll exceed the 505-day report, the researchers stated.

Nebbia stated the state of affairs demonstrated the pressing want for brand spanking new therapies to assist immunocompromised sufferers recuperate.

The findings will probably be offered on the European Congress of Scientific Microbiology and Infectious Ailments in Lisbon, which begins on Saturday.

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