Home NewsAfrica UK Covid-19 patient was positive for record 505 days, researchers say | News24

UK Covid-19 patient was positive for record 505 days, researchers say | News24

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  • The longest recognized Covid-19 an infection has been documented by British researchers.
  • The affected person examined constructive of coronavirus for 505 days earlier than her demise.
  • The affected person examined constructive about 45 occasions earlier than going to hospital.

British researchers consider they’ve documented the longest-known Covid-19 an infection, in a affected person who examined constructive for a complete of 505 days earlier than their demise.

The earlier file for persistent an infection – moderately than repeated bouts of Covid – is regarded as 335 days, the workforce from King’s Faculty London and Man’s and St Thomas’ NHS Basis Belief mentioned.

One of many research’s co-authors, advisor virologist Gaia Nebbia, mentioned the unnamed particular person was recognized in mid-2020 with respiratory signs that later improved.

However they then examined constructive about 45 occasions earlier than attending hospital as much as their demise.

Nebbia mentioned persistent an infection with SARS-CoV-2 – the virus which causes Covid-19 – has been described in sufferers with weakened immune methods.

She and her workforce studied how the virus from 9 Covid-19 sufferers in London modified over time, concluding that new variants might happen in immunocompromised sufferers.

“This is likely one of the hypotheses for the emergence of variants,” Nebbia advised AFP.

Common sampling and genetic evaluation of the virus confirmed that 5 of the 9 sufferers developed not less than one mutation seen in variants of concern. Some people developed a number of mutations related to variants of concern, such because the Alpha, Delta and Omicron variants.

“Nonetheless, not one of the people in our work developed new variants that turned widespread variants of concern.”

Of the 9 immunocompromised sufferers who examined constructive for not less than eight weeks, infections continued on common for 73 days.

However two sufferers had persistent infections for greater than a 12 months.

All of the sufferers had weakened immune methods resulting from organ transplantation, HIV, most cancers or different medical therapies. They have been studied between March 2020 and December final 12 months.

Of the 9, 5 survived. Two of the 5 recovered with out therapy and two others recovered after antibody and antiviral remedy.

The fifth particular person was nonetheless contaminated at their final follow-up examination in early 2022, even after therapy, and had Covid-19 for 412 days.

Ought to they check constructive at their subsequent appointment, they may exceed the 505-day file, the researchers mentioned.

Nebbia mentioned the state of affairs demonstrated the pressing want for brand new remedies to assist immunocompromised sufferers get well.

The findings shall be introduced on the European Congress of Medical Microbiology and Infectious Illnesses in Lisbon, which begins on Saturday.

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